It was modeled after surgical mesh that was in use to repair other tissue damage such as hernia and was designed to be safer than traditional surgical repair methods as the mesh was implanted through the vagina or “transvaginally”. Transvaginal mesh was first introduced in 1996 for the treatment of SUI in women. Transvaginal mesh products manufactured by multiple companies including Endo/AMS for pelvic organ prolapse (POP) and stress urinary incontinence (SUI) may have caused injury to thousands of women and the company still faces many lawsuits. Endo International, AMS, and Transvaginal Mesh Though Endo divested most AMS products and discontinued manufacturing others, Endo may still be responsible for injuries caused by urological devices or products manufactured by AMS including transvaginal mesh and bladder slings. Several testosterone gel manufacturers, including Endo, have faced thousands of testosterone replacement therapy lawsuits. Testopel (testosterone) Pellets for injection.Striant (testosterone) Mucoadhesive for buccal administration.Aveed (testosterone undecanoate) Injection.The company also manufactures several testosterone products including: Paladin Labs – Specialty pharmaceutical development and licensing for CanadaĮndo Pharmaceuticals manufactures popular pain-killer Percocet, along with topical pain medications Lidoderm and Voltaren gel products. The company also formerly manufactured Opana ER, an extended-release oxycodone product which was withdrawn from the market upon FDA request in 2017.Endo Aesthetics – Developed the first FDA-approved injectable treatment for cellulite in the buttocks.Par Pharmaceutical – Generic pharmaceutical and branded injectable products, including authorized generic agreements with a number of pharmaceutical companies.Endo Pharmaceuticals – Brand name pharmaceutical development, manufacturing, and marketing in endocrinology, pain management, and oncology.Endo ProductsĮndo International, plc oversees the operations of four business units including: In 2022, with a crash of Endo stock below $1 a share, Endo International Plc filed for Chapter 11 bankruptcy protection. In 2017, Endo divested Litha Healthcare Group and Grupo Farmaceutico SOMAR. In 2015, Endo completed divestiture of Advanced Medical Supplies (AMS) Men’s Health to Boston Scientific and wound down Astora (formerly AMS) women’s health unit. In 2014, Endo divested HealthTronics and established global headquarters of Endo International plc in Dublin. In 2012, Endo changed the corporate name to Endo Health Solutions. 2014 – Grupo Farmaceutico Somar (SOMAR).2000 – Algos Pharmaceutical Corporation.The company became publicly traded as Endo Pharmaceuticals (ENDP) in 2000 after the merger with Algos Pharmaceutical. In 1998, another big product, Lidoderm was licensed from Hind Healthcare with would mark the beginning of more than two decades of acquisition, mergers, and spinoffs. This included Percocet, Percodan and 10 other licensed products, along with the generics the company had been manufacturing. In 1997, three DuPont executives acquired certain products through a management buyout and purchased the remaining generic division Endo Laboratories, LLC. The Endo division was reestablished as Endo Laboratories in 1994, serving as DuPont Merck’s generic section. du Pont de Nemours and Company to be incorporated into DuPont’s greater business. Endo HistoryĮndo originally began in 1920 as Intravenous Products of America, Inc. Some of these lawsuits have been settled but others remain in court systems. The company was asked to withdraw its extended-release oxycodone product, Opana from the market in 2017 and has faced numerous drug injury and opioid pain medication lawsuits. Therapeutic focus areas of Endo include endocrinology, orthopedics, and urology. headquarters in Malvern, Pennsylvania. The company started as a generic division of DuPont Merck but was split off and has become a global influence through a series of acquisitions and mergers.Endo currently functions as an umbrella organization with multiple business units including Endo Pharmaceuticals, Par Pharmaceutical, Endo Aesthetics and Paladin Labs. Endo is a Dublin, Ireland based company with U.S.
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